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This INHAND document serves as a framework that can be used for the harmonization of diagnostic criteria of hepatic lesions in laboratory rats and mice

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Herceptin Hylecta (trastuzumab/hyaluronidase, Roche/Genentech), Rituxan Hycela (rituximab hyaluronidase, Roche/Genentech), Darzalex Faspro (daratumumab/hyaluronidase, Janssen) and Phesgo (pertuzumab/trastuzumab/hyaluronidase, Roche/Genentech) are examples of SC administered drugs exceeding 2 mL using hyaluronidase co-formulations