Increased GSTP1 expression has been reported in pre-neoplastic lesions in chemically induced animal cancer models (Satoh et al, 1985) and in many human tumours, relative to surrounding normal tissues (Shea et al, 1988)
OXIDATIVE DEFENSE: Synergistic Vitamin C and Alpha-Lipoic Acid (ALA) protect skin cells from UV damage and premature aging
Acta Biochim Pol 50:31936 Zhang D, Lu H, Li J, Shi X, Huang C (2006) Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B
GHK-Cu delivers copper for enzymatic activity Advantages Good cosmetic efficacy data, lipophilic for skin penetration Disadvantages Different mechanism, no copper delivery Peptides Related to GHK-Cu# GHK-Cu occupies a distinctive niche among healing and regenerative peptides due to its dual nature as both a signaling molecule and a copper delivery vehicle
Molecular Weight: 1419.56 g/mol
176 In animal models and cell culture experiments, N-acetyl cysteine enhanced renal excretion of lead (Pb IV), lowered concentrations of mercury, and protected against cadmium-induced liver cell damage