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Final results are expected in late 2026 and could significantly expand tirzepatides FDA-approved cardiovascular indication, mirroring the SELECT breakthrough for semaglutide

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Rybelsus, meanwhile, may suit those who want to trade milder side effects for tighter dosing rules and less powerful effects

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Addition of zebularine and 5-aza-2-deoxycytidine, inhibitors of DNMT activity, blocks the induction of long-term potentiation in hippocampal slices (Levenson et al., 2006)

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