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NRF2 is anchored in the cytoplasm under normal conditions but enters the nucleus and activates antioxidant genes during oxidative stress [28, 29]

Contrary, NP4 showed a cytotoxic effect in the very low micromolar range (143B: IC 50 = 6.6 M, K7M2: IC 50 = 2.1 M) (drug-response curves: Fig

aimed to investigate whether the plasma activities of two antioxidant enzymes, superoxide dismutase (SOD) and glutathione peroxidase (GPx), can be used as diagnostic biomarkers for endometriosis