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Mediators Inflamm (2013) 2013:975032

D., Shepher, M., & Yelvigi, M

Efectos adversos comunes : Los efectos secundarios gastrointestinales son los ms frecuentes, especialmente durante el inicio del tratamiento o aumentos de dosis: Nuseas (reportadas en hasta 44% de pacientes con dosis de 2.4 mg) Vmitos Diarrea Estreimiento Dolor abdominal Estos efectos generalmente disminuyen con el tiempo y pueden minimizarse mediante titulacin gradual de la dosis

Therefore, IGF-1 should not be used alone for the screening of GHD

Since chronic hyperglycemia itself impairs -cell function [12], pharmacologic interventions to reduce hyperglycemia may improve -cell function and restore -cell glucose sensitivity [13]

The slightest variation in its amino acid sequence or the presence of impurities can throw off results entirely