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Ma F, Liu X, Zhang Y, Tao Y, Zhao L, Abusalamah H, et al

Multiple analyses show that when treatment is stopped, most people regain some or all of the weight they lostsometimes moreand that the cardiometabolic benefits do not persist off-drug

The approval also backs up mounting evidence that there could be further health benefits tied to GLP-1s, a class of weight loss and diabetes treatments that have soared in popularity and slipped into shortages over the past year

This suggests key roles for their respective gene products, the E6 and E7 oncoproteins, in inducing malignant transformation [2], [5], [6]

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The drug is known generically as liraglutide, which the FDA says has been in short supply with certain other GLP-1 medications. This references the consistent shortages for drugs like semaglutides, known by brand names such as Ozempic and Wegovy, and tirzepatides, with brand names like Zepbound and Mounjaro