Human trials have predominantly used topical or brief systemic dosing, and tolerability is overall reported to be good
Effects of Tirzepatide on Lipid Profile: A Systematic Review and Meta-Analysis
J., Han, S., Stallings-Mann, M., Radisky, D
GLP-1 receptor agonists are not licensed specifically as anti-inflammatory agents and prescribing follows diabetes and weight management indications under NICE guidance
As the different severity of DR was not well distinguished in the Swedish Patient Register, evaluating the effect of GLP-1 RAs on various severities of DR was not possible in this cohort study
Some healthcare professionals may consider individualised dose titration strategies that balance effective weight loss with muscle preservation, particularly in older adults or those with limited muscle reserves, though evidence specifically for this approach is limited