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doi: 10.14336/AD.2018.0513 284 TufanE.Gksun SivasG.Grel-GkmenB.Ylmaz-KaraoluS.ErcanD.zbeyliD.et al

In REDEFINE 1 (overweight/obesity without T2D), CagriSema achieved mean weight reductions of 20.4-22.7% (vs 2.3-3.0% placebo) at 68 weeks, with 53.6% and 34.7% of patients achieving 20% and 25% weight loss, respectively

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It has to tolerate food, interact with the microbiome, maintain a protective barrier, and respond appropriately to pathogens or injury