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Oncogene 23 : 786794 Acknowledgements Own studies, cited in this review, were supported by grants from the Swedish Cancer Society, the Swedish Research Council, the Cancer Society in Stockholm, the Jubilee Fund of King Gustaf V, the Swedish Children Cancer Society and the Karolinska Institute

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Emerging research points to potential applications in areas such as inflammation and neurological conditions, as well as substance-use disorders, depression, psoriasis, Crohns disease and asthma

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