N Engl J Med 375:18341844 Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pedersen SD, Tack CJ, Thomsen M, Vilsboll T, Warren ML, Bain SC (2019) Oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes
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Some of the most popular medical and cosmetic treatments today are dermal fillers, BOTOX, and semaglutide
Zumaquero warns of diarrhea as the most frequent adverse reaction, in addition to a host of drug interactions, especially with hypoglycemic agents, and adds that if combined with GLP-1 agonists, it can cause hypoglycemia. He also mentions interactions with aspirin, ibuprofen, metformin, and antibiotics. For this reason, he flatly rejects the idea that it can be taken as a general supplement for anyone
Detailed information about side effects can be found in the Patient Information Leaflet (PIL) included with the medication
In addition to supporting appetite suppression and blood sugar control, it may also help increase calorie expenditure and metabolic efficiency through glucagon receptor activation