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Early studies have identified potential side effects, but more evidence is needed before its overall safety can be fully established

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To further evaluate and refine these pathway-level signals, we examined the direction and specificity of individual metabolite changes contributing to enriched pathways 48

These may include diuretics, ACE inhibitors, ARBs, NSAIDs such as ibuprofen, and some diabetes medications

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As your body adjusts to the medication and your calorie intake drops, you may not be getting enough minerals to keep your muscles relaxed, leading to discomfort when you finally rest