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The study published in the JAMA Network Open cited cost as the likely reason, with side effects also mentioned

The rate of adverse cardiovascular outcomes in people with high cardiovascular risk and concomitant CKD is generally 10-fold that of progressive loss of kidney function with the need for dialysis [20]

This is an important consideration for future studies due to the larger effect size in risk of PDAC observed in patients with new onset compared with longstanding diabetes (typically defined as 3 years duration) 46

Unlike many other weight loss methods that may provide short-term results, only to see individuals regain the weight later, Semaglutide offers a different outcome

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However, individual case reports and post-market surveillance have documented AFib episodes in some patients on GLP-1 therapy, particularly during rapid early weight loss phases