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This is not a failure

A parallel line of work by Chang and colleagues (J Appl Physiol, 2011) examined cultured rat Achilles tendon fibroblasts and reported increased outgrowth, survival and migration alongside elevated phosphorylation of focal adhesion kinase (FAK) and paxillin, the adaptor pair coupling integrin engagement to cytoskeletal reorganisation

Objective inflammation assessment: Depending on the clinical situation, assessment may include blood tests, stool markers such as faecal calprotectin, imaging, colonoscopy, gastroscopy or other investigations to understand whether symptoms are linked to active inflammation or another gut condition

This effect was noticeable in IC rats and even more noticeable in IC + RL rats

To evaluate this, the nerve fiber densities in the cornea, proximal thigh and distal leg were assessed