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We therefore applied the ChIP-X Enrichment Analysis 3 (ChEA3) optimization algorithm (49), which isolates the TFs with the largest overlap between a prioritized set of genes for those enzymes and transporters that show the biggest improvement in metabolic adaptability for the largest number of interaction pathways ( Figure 8 )

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How it works: Tesamorelin stimulates the pituitary gland to release growth hormone, which then promotes lipolysis (fat breakdown) particularly in the visceral compartment