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How to store the Ozempic Pen 1 Pen 1 Prior to first use Until expiration date Refrigerated 36 F to 46 F (2 C to 8 C) After first use 56 days Room Temperature 59 F to 86 F (15 C to 30 C) Refrigerated 36 F to 46 F (2 C to 8 C) Learn how to prescribe Ozempic pen Where should the Ozempic pen be injected