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Those who have struggled with insulin resistance or plateaued in their weight loss efforts

Others, particularly those with severe deficiencies or conditions that significantly impair absorption, may benefit more from injections prescribed by their healthcare provider

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This side effect results from semaglutides mechanism of slowing gastrointestinal motility and gastric emptying

Because the elimination half-life is approximately one week and steady-state exposure builds over 4 to 5 weeks of once-weekly administration, exposure declines slowly, which is why the labels specifically contemplate a prolonged period of observation and treatment rather than a short one