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At least one serious adverse event occurred among 10.9% of the 36 mg orforglipron group, 10.3% of the 12 mg orforglipron group, 7.3% of those receiving 6 mg orforglipron and 8.8% of the placebo group

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Compared with the other positive signals, self-induced vomiting was one of the GLP-1 RA-related psychiatric AEs that had a higher ROR signal, but the lowest number of reports ( Figure 3B )

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