Pharmacokinetic scaling across species rodent to larger animal to human extrapolation has not been rigorously published
Some researchers even drop back to the previous dose temporarily before trying the increase again
Instead of taking a single active ingredient, a combination of all of the natural B12 forms is the optimal solution as it mirrors the B12 content in foods
Another study reported BD patients (75 euthymic, 14 manic/hypomanic, 45 depressive) had higher levels of all cytokines, including slL-2R, C-reactive protein (CRP) and sTNFR1 than the healthy controls [73], with depressed BD patients having reduced sTNFRl and slL-2R compared to those in mania and euthymia [73]
Over the years, Ive watched countless patients experience dramatic improvements when BPC was added to their treatment plans
Its rarely a black-and-white, positive-or-negative distinction