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Oral semaglutide versus empagliflozin in patients with type 2 diabetes uncontrolled on metformin: the PIONEER 2 trial

Light, oxygen, and moisture can impact small-molecule stability

and the Takeda Science Foundation (T.H.)

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In the brain, GLP-1Rs are found in several hindbrain and forebrain sites, including areas that are implicated in the control of food intake and regulation of energy balance, such as the area postrema (AP), the nucleus tractus solitarius (NTS), hypothalamus, amygdala, and in the mesolimbic reward system