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These forms are hydrolyzed to produce pyruvate (is an intermediate in several metabolic pathways throughout the cell) and acetaldehyde after being further oxidized to oxaloacetate (Proietti Tocca et al., 2024)

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GAD patients demonstrated broader SCFA depletion, with decreased levels of Faecalibacterium, Eubacterium rectale, Butyricicoccus , and Lachnospira , bacteria integral to maintaining mucosal homeostasis and modulating host-microbiota immune interactions

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Conversely, those with oily or acne-prone skin may benefit more from the gel formulation