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Mechanistically, oxidative stress triggers endoplasmic reticulum stress through the activation of the PERK-eIF2-ATF4 and IRE1-XBP1 signaling pathways, as well as through the upregulation of CHOP (C/EBP homologous protein), which promotes apoptotic signaling (75) as shown in Figure 4

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Sharma R, Singh A, Sharma S (2021) Influence of ozonation on cereal flour functionality and dough characteristics: a review

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