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Gorczyca, A.M

Type 2 diabetes, which is more prevalent and often linked to lifestyle factors, contributes significantly to the market, with treatments focused on oral medications, GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT2 inhibitors

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Because AOD-9604 works peripherally on fat tissue through beta-3 adrenergic receptors without affecting central appetite pathways, there is no adaptation of hunger-regulating systems and therefore no rebound effect when stopping

Over time, it gained recognition for its role in appetite suppression and weight reduction medication strategies

doi: 10.1093/pnasnexus/pgac248 338 RhodesJ.AbdolrasouliA.DunneK.SewellT