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B6 is a rate limiting cofactor in the synthesis of several neurotransmitters such as dopamine, serotonin, -aminobutyric acid (GABA), noradrenaline and the hormone melatonin (1)

-The price increases are not arbitrary they reflect the cost of maintaining pharmaceutical-grade production, complying with strict FDA/USP standards, and meeting high demand in a constrained supply environment

Semaglutide's mechanism of action may affect B12 absorption

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