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To gain further insight, a non-compartmental PK analysis was performed using gPKPDSim 74 , which revealed a 3.8-fold slower clearance rate (CL) and a 2.4-fold longer mean residence time (MRT) of QMP compared with WT albumin (Supplementary Table 4)

Both subspecies have an estimated population size of only about 100 individuals each

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That means these medications have a direct effect on your entire vascular system, not just your blood sugar