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It creates a tingling in the skin, a type of pins and needles, which is technically called paraesthesia

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10.1371/journal.ppat.1011571 33 ChenY.ThaiP.ZhaoY.-H.HoY.-S.DesouzaM

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By the end of the experimental period venous blood samples were collected from the orbital sinus of control and food color treated rats tow fia glass one was containing non agulated material (heparin) for determination hematology and one was used to separation of serum