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Gastrointestinal Side Effects Nausea is the most commonly reported adverse effect across GLP-1 trials, occurring in 44% of semaglutide-treated patients versus 16% with placebo in STEP-1

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Over ~3 years of follow-up, HF risk was markedly higher when prediabetes coexisted with elevated cardiac biomarkers

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31 The initial focus should be on learning the movements correctly rather than lifting the heaviest possible weight