Four studies have shown significant improvements in liver function markers such as aminotransferases (AST/ALT), albumin, and oxidative stress markers (e.g., malondialdehyde) when compared to placebo
Bossart M, Wagner M, Elvert R, Evers A, Hbschle T, Kloeckener T, et al
Huang S, Lin L, Wang S, Ding W, Zhang C, Shaukat A, et al
On the other hand, they do not appear to increase pulse frequency or cause supraphysiological GH levels [7, 12]
By day three to five of multi-dose use after multiple needle punctures have introduced skin-flora organisms through the rubber stopper microbial counts begin to climb
So the question remains whether lower-and-middle income countries, which are facing their own accelerating obesity rates, will have the same level of access