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Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2

Hypertension and oxidative stress

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The specific metabolic benefit appears to result from gut bacteria modifications, increased Bifidobacterium and decreased Firmicutes species

+ The calculations use standard pharmaceutical formulas: concentration (mg/mL) = vial size water volume, and draw volume (mL) = target dose concentration