Even though higher doses of oral semaglutide (25 mg and 50 mg) can achieve similar HbA 1c and weight reductions to orforglipron, the convenience of unrestricted daily orforglipron dosing means this is likely to be more attractive to people requesting an oral drug, depending on whether cardiovascular benefits are observed in the outcomes study
(2024, June 18)
Can Heart Palpitations Seriously Affect My Health As An Ozempic Patient
Some people find cold brew causes less stomach irritation than hot coffee, simply because of the lower acid content
Further randomised trials are recommended to confirm these findings and explore higher doses
There is some evidence that GLP-1s might decrease collagen and moisture levels in the skin, for example, by turning off adipose-derived stem cells which, would otherwise stimulate fibroblasts in the skin to produce collagen, elastin, and hyaluronic acid, Steven Dayan, MD, a board-certified plastic surgeon in Chicago who has researched the impact of GLP-1s on skin, has told Allure