It is a recognized medical disorder rooted in neurochemical signaling within the central nervous system , particularly in the hypothalamus and related brain regions that regulate motivation and reward
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It often reflects deeper issues such as reduced cellular energy, inflammation, or nutrient deficiencies
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The study researchers noted that this could be a tool for severely symptomatic patients, but that further research was needed to understand its efficacy
J Cell Biol 123:12691277 Perez H, Arredondo B, Gonzalez M (1978) Comparative study of American cutaneous leishmaniasis and diffuse cutaneous leishmaniasis in two strains of inbred mice
