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Gastroenterology 164, 550566
These labels were written before the human lactation studies were published
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Participants received either 12mg or 36mg of orforglipron, or 7mg or 14mg of oral semaglutide, over the course of a year
Unlike endogenous GLP-1, which has a half-life of only 12 minutes due to rapid degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), exendin-4 exhibits resistance to DPP-4 breakdown
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