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Multiple liver transplant cases documented at supratherapeutic doses (6-9 grams/day) with fetal death

doi: 10.1111/obr.12334 6 HannonTSArslanianSA

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evaluated the efficacy of semaglutide in patients with MASH in a 72-week, randomized, double-blind phase II trial involving 320 patients, and semaglutide 0.4 mg daily led to MASH resolution without worsening fibrosis in 59% of patients, compared to 17% with placebo

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