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For example, elevated levels of IL-6 and TNF- can disrupt serotonin metabolism by promoting activation of the kynurenine pathway, which diverts tryptophan away from serotonin synthesis and towards the production of neuroactive metabolites (quinolinic acid (QUIN)) [157,158]

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Addressing these deficiencies through dietary modifications or supplementation has the potential to improve patients' outcomes by strengthening immune function, mitigating treatment-related side effects, and enhancing overall quality of life

doi: 10.1039/C6FO01770C 542 PierettiSRanjanAPDi GiannuarioAMukerjeeAMarzoliFDi GiovannandreaRet al

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