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From a therapeutic standpoint, their main opportunity may be combination design: pairing ferroptosis induction with interventions that remodel mitochondrial electron flow or substrate availability, thereby constraining the capacity to regenerate CoQ 10 H 2

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Such efforts will accelerate the scientific development of TCM and provide a stronger, evidence-based foundation for clinical applications [671]

10.1080/26895293.2020.1781698 42 IbrahimA

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