This means it can help break down mucus, supporting clear and healthy respiratory function
hence, it can be recommended as adjuvant therapy alongside MTX to counteract its cytotoxic adverse effects
Although the etiology of IBD remains unclear, it is generally considered to be the result of a confluence of environmental factors (such as nutrition and microbiota), immune system dysregulation, intestinal epithelial barrier impairment, and genetic predisposition (178)
These injections are administered directly into the hip muscle for increased absorption
Clinical trials vs real-world results What the clinical trials show The landmark SURMOUNT-5 trial published in 2025 compared these medications directly at standard maximum doses: 1 Mounjaro (tirzepatide 15 mg) produced 20.2% average weight loss Wegovy (semaglutide 2.4 mg) produced 13.7% average weight loss The 6.5 percentage point difference was statistically significant This trial used the maximum approved doses at the time (Mounjaro 15 mg, Wegovy 2.4 mg) and lasted 72 weeks
Private clinics can provide access for weight management, but cost is a consideration