Categorization of patients The CKD status of patients at baseline was determined according to KDIGO guidelines, where a combined variable consisting of eGFR [six categories ranging from normal/high eGFR (G1, 90 mL/min/1.73 m 2 ) to kidney failure (G5, 300 mg/g)] is considered ( Supplementary Table 1 ) ( Collected variables The following data were collected at baseline, and at the 6- and 12-month follow-up visits: anthropometric parameters, namely, weight, body mass index (BMI), waist circumference, and blood pressure
Code availability Data processing and statistical analyses were performed using the open-source software R (version 4.5.1)
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Of these 20, 9 are referred to as essential amino acids because they cannot be produced by the body and so must be obtained from dietary sources
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This observation is, in fact, backed by a 4-week scientific study conducted by the National Center for Biotechnology Information (NCBI)