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Cu(II) binding to this site is reversible, however, characterized by slow unassisted dissociation rate and picomolar affinity ( K D = 0.90 0.09 pM), determined with NTA or fast and His-assisted dissociation and apparent subpicomolar affinity ( K D = 34.7 4.5 fM)

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10.1152/AJPLUNG.1994.266.4.L405 247 SilvaI

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