tachycardia, tachypnoea, altered level of consciousness presence of risk factors features of underlying cause INVESTIGATIONS high anion gap metabolic acidosis (HAGMA) on blood gas normal osmolar gap normal lactate normal beta-hydroxybutyrate high pyroglutamic acid (urine or blood) MANAGEMENT stop exacerbating factors treat sepsis, including: early and appropriate antibiotics source control supportive care and monitoring intubation, ventilation, renal replacement therapy (RRT) as indicated N-acetylcysteine help replenish glutathione stores References and Links LITFL Metabolic Muddle 004 Staph sepsis and an unusual metabolic acidosis Journal articles Dempsey GA, Lyall HJ, Corke CF, & Scheinkestel CD (2000)
Certificate of Analysis Research Use Only These studies reference research-grade peptides for laboratory and scientific investigation only
Analytical records should be reviewed as documentation, not as product-performance proof [17] [20]
Common conditions such as diabetes, obesity, mental health disorders, and metabolic dysfunctions are poised to reap the greatest rewards from this new era in drug discovery
doi:10.1186/1471-244x-12-107 Enriquez-Geppert S, Smit D, Pimenta MG, Arns M
MacDonald-Hull, S
