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Common side effects include: Gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation) Decreased appetite and potential malnutrition in vulnerable individuals Risk of hypoglycemia when combined with insulin or sulfonylureas Rare but serious risks including pancreatitis and gallbladder disease Important safety considerations include: Boxed warning for thyroid C-cell tumors in rodents

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*Correspondence: Cyriac Abby Philips, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Benjamin Brown has received consultancy fees from Pure Encapsulations (Sudbury, MA, USA)

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