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Immediate post-injection care focuses on minimising local reactions: Apply a cold compress to the injection site for 1015 minutes to reduce pain and swelling Avoid massaging or rubbing the area, which can increase bruising Wear loose clothing that doesn't irritate the injection site Gentle movement of the affected limb may help reduce stiffness Hydration and nutrition support general wellbeing during treatment

doi: 10.1038/cdd.2013.180 101 JuckerM.WalkerL

du Preez, H

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The cause of skin necrosis is tissue hypoxia or ischemia as well as bacterial infection

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