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Nicotine interacts with the receptors in the brain, which triggers the release of dopamine

Primary research encompassed over 55 structured interviews conducted in 2024-2025 with e-cigarette brand managers, vape specialty retail buyers, regulatory affairs directors at tobacco multinationals, ASH (Action on Smoking and Health) policy specialists, FDA Center for Tobacco Products analysts, and equity analysts covering tobacco and alternative nicotine sectors

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