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For example, senescent T-cells are accumulated in visceral adipose tissues in obesity 67 and produce proinflammatory cytokines, leading to chronic inflammation, metabolic disorders, and cardiovascular diseases 68,69

Elevated levels of circulating biomarkers associated with oxidative stress and mitochondrial damage, such as F2-isoprostanes, malondialdehyde, and reduced levels of antioxidants like coenzyme Q10, have been reported [20, 21, 44,45,46,47,48]

Poster presented at: American Headache Society Virtual Annual Scientific Meeting, June 3-6, 2021

doi:10.1007/s00726-017-2389-2 [19] Dinicola S, De Grazia S, Carlomagno G, Pintucci JP.N-acetylcysteine as powerful molecule to destroy bacterial biofilms

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