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SNAC exposure did increase with decreases in hepatic function, with the greatest increase seen in patients with severe hepatic impairment (3.64 times higher than patients with normal hepatic function)

In turn, they may cause appetite changes and promote lower calorie intake, which may help support weight loss alongside diet and activity

This can influence the bodys susceptibility to toxins

Conclusions In conclusion, evidence on CHE has advanced substantially over the past two decades, highlighting its growing importance in cirrhosis care

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2017;39(8S2):S111