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Once unfolded, it does not refold correctly

Community protocols hold each step at least 4 weeks and step back if GI side effects are intense

Say goodbye to the days of double cleansing

The technical basis is more concrete: foam holds liquid on vertical surfaces long enough to dissolve soap scum and limescale

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de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, Gravis G, Bodrogi I, Mackenzie MJ, Shen L, Roessner M, Gupta S, Sartor AO (2010) Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial