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However, neurotrophins have had little success in clinical trials directed at neurodegenerative diseases due to their poor pharmokinetic profile and large molecular weight that significantly impedes penetration of the BBB [61,62]

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Here we suggest that desensitization be used only to describe acute loss of MOR-effector coupling that occurs within seconds to minutes after initiation of exposure to opioid agonists

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Neuroprotective and Cardioprotective Effects BPC-157 helps protect your brain and heart by supporting the health of the neural and cardiovascular systems