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15 This cascade of events is accompanied by increased oxidative stress, another postulated effect of chronically elevated TMAO levels, observed also in healthy individuals

Moreover, TMAO disrupts the renal tubular transport system by inhibiting organic cation and anion transporters (OCTs and OATs), essential for reabsorbing and secreting various compounds in the kidneys (Samodelov et al., 2020)

Este transportador es la L-Carnitina gracias a la cual los cidos grasos activados son desviados hacia la oxidacin y no se emplean por el organismo en la neoformacin de TGC (triglicridos), habiendo as menos biodisponibilidad plasmtica de cidos grasos activados

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