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Sequest-HT was searched with a fragment ion mass tolerance of 0.20 Da and a parent ion tolerance of 10.0 PPM

The use of vitamin E supplements may increase the risk of bleeding in individuals taking anticoagulant drugs (blood thinners), such as heparin and the vitamin K antagonist, warfarin (Coumadin)

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Specifically, preclinical studies tend to batch collect and process samples, whereas clinical studies tend to collect and process samples one at a time

However, since catecholamine depletion takes some time to develop , reserpine-like drugs must be given several hours to days in advance of tyramine for this interaction to be observable