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However, its important to note that there is still not enough solid evidence to give 100% certainty that taking vitamin B12 will reduce your risk of heart disease

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How to Titrate, and the Consequences of Increasing Too Quickly The final dose shapes the endpoint, but titration determines whether that dose remains tolerable

So if they get to the point that they aren't eating for a day or two it's important to make an appointment with your vet right away

Your provider may give you specific instructions according to your individual needs