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Further studies revealed that DPP4 acts as a binding protein for adenosine deaminase (ADA) and serves as a T cell activation marker, transmitting co-stimulatory signals upon ADA stimulation

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Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome

Splitting a 2.5 mg starting dose is rarely necessary and adds complexity during the learning phase

The peptide has also never been characterized in humans the way an approved drug is: there is no established human pharmacokinetic profile, no dose-ranging efficacy study, and no long-term safety dataset