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A 2021 cohort study published in JAMA Dermatology (Droitcourt et al., JAMA Dermatol

Both sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) create direct or indirect functional bypasses that accelerate nutrient delivery

The information in this post is not intended to substitute medical advice, diagnosis or treatment and should not be exclusively relied on to diagnose or manage a medical condition

However, it raises an interesting thought that maybe the benefit of SGLT-2 inhibitors on endothelial function, mediated by nitric oxide, may improve vasodilation of the pulmonary vasculature while reducing insulin resistance, elevated blood glucose, and obesity [105]

You might have one or two episodes of loose stools daily during the adjustment period

Potential Downsides and Unknowns Long-term safety : Retatrutide is still in trials, so long-term LDL and cardiovascular outcomes arent confirmed